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Transport dynamics in a glutamate transporter homologue

Glutamate transporters are integral membrane proteins that catalyze neurotransmitter uptake from the synaptic cleft into the cytoplasm of glial cells and neurons(1). Their mechanism involves transitions between extracellular- (outward-) and intracellular- (inward-) facing conformations, whereby subs...

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Detalles Bibliográficos
Autores principales: Akyuz, Nurunisa, Altman, Roger B., Blanchard, Scott C., Boudker, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829612/
https://www.ncbi.nlm.nih.gov/pubmed/23792560
http://dx.doi.org/10.1038/nature12265