Hypoxia- and radiation-induced overexpression of Smac by an adenoviral vector and its effects on cell cycle and apoptosis in MDA-MB-231 human breast cancer cells

A conditionally replicative adenoviral (CRAd) vector, designated as CRAd.pEgr-1-Smac, that promotes the overexpression of second mitochondria-derived activator of caspase (Smac) when stimulated by hypoxia and radiation was constructed. MDA-MB-231 cells were transfected with CRAd.pEgr-1-Smac and trea...

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Detalles Bibliográficos
Autores principales: LIU, WEI-WU, LIU, YANG, LIANG, SHUO, WU, JIA-HUI, WANG, ZHI-CHENG, GONG, SHOU-LIANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829727/
https://www.ncbi.nlm.nih.gov/pubmed/24255691
http://dx.doi.org/10.3892/etm.2013.1351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829727/
https://www.ncbi.nlm.nih.gov/pubmed/24255691
http://dx.doi.org/10.3892/etm.2013.1351

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