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Apolipoprotein E gene polymorphism influences aggressive behavior in prostate cancer cells by deregulating cholesterol homeostasis

High circulating cholesterol and its deregulated homeostasis may facilitate prostate cancer progression. Genetic polymorphism in Apolipoprotein (Apo) E, a key cholesterol regulatory protein may effect changes in systemic cholesterol levels. In this investigation, we determined whether variants of th...

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Detalles Bibliográficos
Autores principales: IFERE, GODWIN O., DESMOND, RENEE, DEMARK-WAHNEFRIED, WENDY, NAGY, TIM R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 201
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829771/
https://www.ncbi.nlm.nih.gov/pubmed/23934233
http://dx.doi.org/ 10.3892/ijo.2013.2057