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Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in pediatric human sarcoma cell lines

Pediatric sarcomas are highly aggressive tumors that are characterized by high levels of matrix metalloproteinase (MMP)-2 and -9 secretions that degrade the ECM and basement membrane, allowing cancer cells to spread to distal organs. Proteases play a key role in tumor cell invasion and metastasis by...

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Detalles Bibliográficos
Autores principales: ROOMI, M. WAHEED, KALINOVSKY, TATIANA, NIEDZWIECKI, ALEKSANDRA, RATH, MATTHIAS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 201
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829799/
https://www.ncbi.nlm.nih.gov/pubmed/23900236
http://dx.doi.org/ 10.3892/ijo.2013.2031