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The ENTPD5/mt-PCPH oncoprotein is a catalytically inactive member of the ectonucleoside triphosphate diphosphohydrolase family

Expression of the ENTPD5/mt-PCPH onco-protein and overexpression of the normal ENTPD5/PCPH protein contribute to the malignant transformation of diverse mammalian cell types, and PCPH is mutated and/or deregulated in various human tumor types. Expression of PCPH or mt-PCPH caused similar phenotypes,...

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Detalles Bibliográficos
Autores principales: MacCARTHY, CAITLIN M., NOTARIO, VICENTE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 201
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829800/
https://www.ncbi.nlm.nih.gov/pubmed/23921441
http://dx.doi.org/ 10.3892/ijo.2013.2052