Myriocin Significantly Increases the Mortality of a Non-Mammalian Model Host during Candida Pathogenesis

Candida albicans is a major human pathogen whose treatment is challenging due to antifungal drug toxicity, drug resistance and paucity of antifungal agents available. Myrocin (MYR) inhibits sphingosine synthesis, a precursor of sphingolipids, an important cell membrane and signaling molecule compone...

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Detalles Bibliográficos
Autores principales: de Melo, Nadja Rodrigues, Abdrahman, Ahmed, Greig, Carolyn, Mukherjee, Krishnendu, Thornton, Catherine, Ratcliffe, Norman A., Vilcinskas, Andreas, Butt, Tariq M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829820/
https://www.ncbi.nlm.nih.gov/pubmed/24260135
http://dx.doi.org/10.1371/journal.pone.0078905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829820/
https://www.ncbi.nlm.nih.gov/pubmed/24260135
http://dx.doi.org/10.1371/journal.pone.0078905

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