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Myriocin Significantly Increases the Mortality of a Non-Mammalian Model Host during Candida Pathogenesis
Candida albicans is a major human pathogen whose treatment is challenging due to antifungal drug toxicity, drug resistance and paucity of antifungal agents available. Myrocin (MYR) inhibits sphingosine synthesis, a precursor of sphingolipids, an important cell membrane and signaling molecule compone...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829820/ https://www.ncbi.nlm.nih.gov/pubmed/24260135 http://dx.doi.org/10.1371/journal.pone.0078905 |