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Aquaporin-4 Autoantibodies in Neuromyelitis Optica: AQP4 Isoform-Dependent Sensitivity and Specificity

Neuromyelitis Optica (NMO) is an autoimmune demyelinating disease, characterized by the presence of autoantibody (NMO-IgG) to Aquaporin-4 (AQP4). NMO-IgG identification supports NMO diagnosis and several diagnostic tests have been developed, but their sensitivity is too variable, and some assay show...

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Detalles Bibliográficos
Autores principales: Pisani, Francesco, Sparaneo, Angelo, Tortorella, Carla, Ruggieri, Maddalena, Trojano, Maria, Mola, Maria Grazia, Nicchia, Grazia Paola, Frigeri, Antonio, Svelto, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829826/
https://www.ncbi.nlm.nih.gov/pubmed/24260168
http://dx.doi.org/10.1371/journal.pone.0079185