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New Function of the Adaptor Protein SH2B1 in Brain-Derived Neurotrophic Factor-Induced Neurite Outgrowth

Neurite outgrowth is an essential process for the establishment of the nervous system. Brain-derived neurotrophic factor (BDNF) binds to its receptor TrkB and regulates axonal and dendritic morphology of neurons through signal transduction and gene expression. SH2B1 is a signaling adaptor protein th...

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Detalles Bibliográficos
Autores principales: Shih, Chien-Hung, Chen, Chien-Jen, Chen, Linyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829828/
https://www.ncbi.nlm.nih.gov/pubmed/24260264
http://dx.doi.org/10.1371/journal.pone.0079619