Impaired Spatial Learning and Memory after Sevoflurane–Nitrous Oxide Anesthesia in Aged Rats Is Associated with Down-Regulated cAMP/CREB Signaling

Neurocognitive deficits arising from anesthetic exposure have recently been debated, while studies have shown that the phosphorylation of cyclic AMP response element-binding protein (CREB) in the hippocampus is critical for long-term memory. To better understand the neural effects of inhalational an...

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Detalles Bibliográficos
Autores principales: Xiong, Wan-Xia, Zhou, Guo-Xia, Wang, Bei, Xue, Zhang-Gang, Wang, Lu, Sun, Hui-Chuan, Ge, Sheng-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829840/
https://www.ncbi.nlm.nih.gov/pubmed/24260214
http://dx.doi.org/10.1371/journal.pone.0079408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829840/
https://www.ncbi.nlm.nih.gov/pubmed/24260214
http://dx.doi.org/10.1371/journal.pone.0079408

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