Cargando…

Alzheimer’s Disease Susceptibility Genes APOE and TOMM40, and Hippocampal Volumes in the Lothian Birth Cohort 1936

The APOE ε and TOMM40 rs10524523 (‘523’) variable length poly-T repeat gene loci have been significantly and independently associated with Alzheimer’s disease (AD) related phenotypes such as age of clinical onset. Hippocampal atrophy has been significantly associated with memory impairment, a charac...

Descripción completa

Detalles Bibliográficos
Autores principales: Lyall, Donald M., Royle, Natalie A., Harris, Sarah E., Bastin, Mark E., Maniega, Susana Muñoz, Murray, Catherine, Lutz, Michael W., Saunders, Ann M., Roses, Allen D., del Valdés Hernández, Maria C., Starr, John M., Porteous, David. J., Wardlaw, Joanna M., Deary, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829876/
https://www.ncbi.nlm.nih.gov/pubmed/24260406
http://dx.doi.org/10.1371/journal.pone.0080513