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Alzheimer’s Disease Susceptibility Genes APOE and TOMM40, and Hippocampal Volumes in the Lothian Birth Cohort 1936
The APOE ε and TOMM40 rs10524523 (‘523’) variable length poly-T repeat gene loci have been significantly and independently associated with Alzheimer’s disease (AD) related phenotypes such as age of clinical onset. Hippocampal atrophy has been significantly associated with memory impairment, a charac...
Autores principales: | Lyall, Donald M., Royle, Natalie A., Harris, Sarah E., Bastin, Mark E., Maniega, Susana Muñoz, Murray, Catherine, Lutz, Michael W., Saunders, Ann M., Roses, Allen D., del Valdés Hernández, Maria C., Starr, John M., Porteous, David. J., Wardlaw, Joanna M., Deary, Ian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829876/ https://www.ncbi.nlm.nih.gov/pubmed/24260406 http://dx.doi.org/10.1371/journal.pone.0080513 |
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