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Altered Expression of Polycomb Group Genes in Glioblastoma Multiforme

The Polycomb group (PcG) proteins play a critical role in histone mediated epigenetics which has been implicated in the malignant evolution of glioblastoma multiforme (GBM). By systematically interrogating The Cancer Genome Atlas (TCGA), we discovered widespread aberrant expression of the PcG member...

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Detalles Bibliográficos
Autores principales: Li, Gang, Warden, Charles, Zou, Zhaoxia, Neman, Josh, Krueger, Joseph S., Jain, Alisha, Jandial, Rahul, Chen, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829908/
https://www.ncbi.nlm.nih.gov/pubmed/24260522
http://dx.doi.org/10.1371/journal.pone.0080970