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Beta-Catenin/HuR Post-Transcriptional Machinery Governs Cancer Stem Cell Features in Response to Hypoxia

Hypoxia has been long-time acknowledged as major cancer-promoting microenvironment. In such an energy-restrictive condition, post-transcriptional mechanisms gain importance over the energy-expensive gene transcription machinery. Here we show that the onset of hypoxia-induced cancer stem cell feature...

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Detalles Bibliográficos
Autores principales: D’Uva, Gabriele, Bertoni, Sara, Lauriola, Mattia, De Carolis, Sabrina, Pacilli, Annalisa, D’Anello, Laura, Santini, Donatella, Taffurelli, Mario, Ceccarelli, Claudio, Yarden, Yosef, Montanaro, Lorenzo, Bonafé, Massimiliano, Storci, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829939/
https://www.ncbi.nlm.nih.gov/pubmed/24260469
http://dx.doi.org/10.1371/journal.pone.0080742