RIN1 regulates cell migration through RAB5 GTPases and ABL tyrosine kinases

Stimulation of a receptor tyrosine kinase (RTK), such as EGFR, leads to RAS activation followed by RIN1 activation. RIN1, in turn, activates RAB5 family GTPases, as well as ABL tyrosine kinases. As expected, RIN1 expression directly correlates with RAB5-mediated EGFR endocytosis. We previously showe...

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Detalles Bibliográficos
Autores principales: Balaji, Kavitha, Colicelli, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829955/
https://www.ncbi.nlm.nih.gov/pubmed/24265854
http://dx.doi.org/10.4161/cib.25421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829955/
https://www.ncbi.nlm.nih.gov/pubmed/24265854
http://dx.doi.org/10.4161/cib.25421

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