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Cellular Effects of Everolimus and Sirolimus on Podocytes

Everolimus (EVL) and Sirolimus (SRL) are potent immunosuppressant agents belonging to the group of mammalian target of rapamycin (mTOR) inhibitors used to prevent transplant rejection. However, some patients develop proteinuria following a switch from a calcineurin inhibitor regimen to mTOR inhibito...

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Detalles Bibliográficos
Autores principales: Müller-Krebs, Sandra, Weber, Lena, Tsobaneli, Julia, Kihm, Lars P., Reiser, Jochen, Zeier, Martin, Schwenger, Vedat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829970/
https://www.ncbi.nlm.nih.gov/pubmed/24260371
http://dx.doi.org/10.1371/journal.pone.0080340