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Diet-induced obesity induces endoplasmic reticulum stress and insulin resistance in the amygdala of rats()
Insulin acts in the hypothalamus, decreasing food intake (FI) by the IR/PI3K/Akt pathway. This pathway is impaired in obese animals and endoplasmic reticulum (ER) stress and low-grade inflammation are possible mechanisms involved in this impairment. Here, we highlighted the amygdala as an important...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829990/ https://www.ncbi.nlm.nih.gov/pubmed/24251109 http://dx.doi.org/10.1016/j.fob.2013.09.002 |