Mutations of an NAD(P)H-dependent flavoprotein monooxygenase that influence cofactor promiscuity and enantioselectivity()

The flavoprotein monooxygenase (FPMO) from Stenotrophomonas maltophilia (SMFMO, Uniprot: B2FLR2) catalyses the asymmetric oxidation of thioethers and is unusual amongst FPMOs in its ability to use the non-phosphorylated cofactor NADH, as well as NADPH, for the reduction of the FAD coenzyme. In order...

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Detalles Bibliográficos
Autores principales: Jensen, Chantel N., Ali, Sohail T., Allen, Michael J., Grogan, Gideon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829993/
https://www.ncbi.nlm.nih.gov/pubmed/24251114
http://dx.doi.org/10.1016/j.fob.2013.09.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829993/
https://www.ncbi.nlm.nih.gov/pubmed/24251114
http://dx.doi.org/10.1016/j.fob.2013.09.008

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