A serially coupled stationary phase method for the determination of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine by liquid chromatography ion trap tandem mass spectrometry()

Oxidative attack to DNA is of particular interest since DNA modifications can lead to heritable mutations. The most studied product of DNA oxidation is 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG). While 8-oxodG determination in blood and tissue cells is prone to artifacts, its measurement in urine...

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Detalles Bibliográficos
Autores principales: Rota, Cristina, Cristoni, Simone, Trenti, Tommaso, Cariani, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830056/
https://www.ncbi.nlm.nih.gov/pubmed/24251117
http://dx.doi.org/10.1016/j.redox.2013.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830056/
https://www.ncbi.nlm.nih.gov/pubmed/24251117
http://dx.doi.org/10.1016/j.redox.2013.10.001

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