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Should leptin replace insulin as a lifetime monotherapy for diabetes type 1 and 2?
Evidence accumulated during the last decade has affirmed that adipocyte leptin insufficiency in the hypothalamus is the primary etiological factor in the pathogenesis of diabetes type 1 and 2 and related metabolic morbidities. Leptin insufficiency disrupts the relay of hypothalamic regulatory inform...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830314/ https://www.ncbi.nlm.nih.gov/pubmed/24251168 http://dx.doi.org/10.4103/2230-8210.119496 |