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Pharmacodynamic study of Disulfiram in Men with Non-metastatic Recurrent Prostate Cancer
BACKGROUND: Preclinical drug screens identified disulfiram as a potent in vitro inhibitor of prostate cancer cell growth. Although many mechanisms for its anticancer activity have been proposed, tumor suppressor gene re-expression through promoter demethylation emerged as one of the more plausible....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830644/ https://www.ncbi.nlm.nih.gov/pubmed/23958896 http://dx.doi.org/10.1038/pcan.2013.28 |