Cargando…

Pharmacodynamic study of Disulfiram in Men with Non-metastatic Recurrent Prostate Cancer

BACKGROUND: Preclinical drug screens identified disulfiram as a potent in vitro inhibitor of prostate cancer cell growth. Although many mechanisms for its anticancer activity have been proposed, tumor suppressor gene re-expression through promoter demethylation emerged as one of the more plausible....

Descripción completa

Detalles Bibliográficos
Autores principales: Schweizer, Michael T., Lin, Jianqing, Blackford, Amanda, Bardia, Aditya, King, Serina, Armstrong, Andrew J., Rudek, Michelle A., Yegnasubramanian, Srinivasan, Carducci, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830644/
https://www.ncbi.nlm.nih.gov/pubmed/23958896
http://dx.doi.org/10.1038/pcan.2013.28