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Low pH Environmental Stress Inhibits LPS and LTA-Stimulated Proinflammatory Cytokine Production in Rat Alveolar Macrophages

Gastric aspiration increases the risks for developing secondary bacterial pneumonia. Cytokine elaboration through pathogen recognition receptors (PRRs) is an important mechanism in initiating innate immune host response. Effects of low pH stress, a critical component of aspiration pathogenesis, on t...

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Detalles Bibliográficos
Autores principales: Fernandez, Stanley F., Fung, Christopher, Helinski, Jadwiga D., Alluri, Ravi, Davidson, Bruce A., Knight, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830824/
https://www.ncbi.nlm.nih.gov/pubmed/24288685
http://dx.doi.org/10.1155/2013/742184