CD8 Knockout Mice Are Protected from Challenge by Vaccination with WR201, a Live Attenuated Mutant of Brucella melitensis

CD8+ T cells have been reported to play an important role in defense against B. abortus infection in mouse models. In the present report, we use CD8 knockout mice to further elucidate the role of these cells in protection from B. melitensis infection. Mice were immunized orally by administration of...

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Detalles Bibliográficos
Autores principales: Yingst, Samuel L., Izadjoo, Mina, Hoover, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830850/
https://www.ncbi.nlm.nih.gov/pubmed/24288554
http://dx.doi.org/10.1155/2013/686919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830850/
https://www.ncbi.nlm.nih.gov/pubmed/24288554
http://dx.doi.org/10.1155/2013/686919

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