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RNA Interference Targeting Connective Tissue Growth Factor Inhibits the Transforming Growth Factor-β (2) Induced Proliferation in Human Tenon Capsule Fibroblasts

Purpose. This study was to determine the effect of CTGF-small interfering RNA (siRNA) on TGF-β (2)-induced proliferation in human Tenon capsule fibroblasts (HTFs). Methods. HTFs were transfected with four of CTGF-siRNAs separately for screening of gene silencing efficacy that was determined by trans...

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Detalles Bibliográficos
Autores principales: Jing, Jiaona, Li, Ping, Li, Tiejun, Sun, Yuncheng, Guan, Huaijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830853/
https://www.ncbi.nlm.nih.gov/pubmed/24288593
http://dx.doi.org/10.1155/2013/354798