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Generation of Mature N(α)-Terminal Acetylated Thymosin α1 by Cleavage of Recombinant Prothymosin α
N(α)-terminal acetylation of peptides plays an important biological role but is rarely observed in prokaryotes. N(α)-terminal acetylated thymosin α1 (Tα1), a 28-amino-acid peptide, is an immune modifier that has been used in the clinic to treat hepatitis B and C virus (HBV/HCV) infections. We previo...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830889/ https://www.ncbi.nlm.nih.gov/pubmed/24288480 http://dx.doi.org/10.1155/2013/387282 |