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Generation of Mature N(α)-Terminal Acetylated Thymosin α1 by Cleavage of Recombinant Prothymosin α

N(α)-terminal acetylation of peptides plays an important biological role but is rarely observed in prokaryotes. N(α)-terminal acetylated thymosin α1 (Tα1), a 28-amino-acid peptide, is an immune modifier that has been used in the clinic to treat hepatitis B and C virus (HBV/HCV) infections. We previo...

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Detalles Bibliográficos
Autores principales: Liu, Bo, Gong, Xin, Chang, Shaohong, Sun, Peng, Wu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830889/
https://www.ncbi.nlm.nih.gov/pubmed/24288480
http://dx.doi.org/10.1155/2013/387282