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An Infection-enhanced Oncolytic Adenovirus Secreting H. pylori Neutrophil-activating Protein with Therapeutic Effects on Neuroendocrine Tumors

Helicobacter pylori neutrophil-activating protein (HP-NAP) is a major virulence factor involved in H. pylori infection. HP-NAP can mediate antitumor effects by recruiting neutrophils and inducing Th1-type differentiation in the tumor microenvironment. It therefore holds strong potential as a therape...

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Detalles Bibliográficos
Autores principales: Ramachandran, Mohanraj, Yu, Di, Wanders, Alkwin, Essand, Magnus, Eriksson, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831034/
https://www.ncbi.nlm.nih.gov/pubmed/23817216
http://dx.doi.org/10.1038/mt.2013.153