Cargando…

Vaccinia Virus Induces Programmed Necrosis in Ovarian Cancer Cells

The mechanisms by which oncolytic vaccinia virus induces tumor cell death are poorly understood. We have evaluated cell death pathways following infection of ovarian cancer cells with both wild-type and thymidine kinase-deleted (dTK) Lister strain vaccinia. We show that death does not rely upon clas...

Descripción completa

Detalles Bibliográficos
Autores principales: Whilding, Lynsey M, Archibald, Kyra M, Kulbe, Hagen, Balkwill, Frances R, Öberg, Daniel, McNeish, Iain A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831043/
https://www.ncbi.nlm.nih.gov/pubmed/23985697
http://dx.doi.org/10.1038/mt.2013.195