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PftetQ and pfmdt copy numbers as predictive molecular markers of decreased ex vivo doxycycline susceptibility in imported Plasmodium falciparum malaria

BACKGROUND: The objective of this study was to evaluate the distribution of a series of independent doxycycline inhibitory concentration 50% (IC(50)) values to validate the trimodal distribution previously described and to validate the use of the pftetQ and pfmdt genes as molecular markers of decrea...

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Detalles Bibliográficos
Autores principales: Gaillard, Tiphaine, Briolant, Sébastien, Houzé, Sandrine, Baragatti, Meïli, Wurtz, Nathalie, Hubert, Véronique, Lavina, Morgane, Pascual, Aurélie, Travaillé, Christelle, Le Bras, Jacques, Pradines, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831056/
https://www.ncbi.nlm.nih.gov/pubmed/24225377
http://dx.doi.org/10.1186/1475-2875-12-414