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Properties of permutation-based gene tests and controlling type 1 error using a summary statistic based gene test

BACKGROUND: The advent of genome-wide association studies has led to many novel disease-SNP associations, opening the door to focused study on their biological underpinnings. Because of the importance of analyzing these associations, numerous statistical methods have been devoted to them. However, f...

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Detalles Bibliográficos
Autores principales: Swanson, David M, Blacker, Deborah, AlChawa, Taofik, Ludwig, Kerstin U, Mangold, Elisabeth, Lange, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831057/
https://www.ncbi.nlm.nih.gov/pubmed/24199751
http://dx.doi.org/10.1186/1471-2156-14-108