The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia(1)(2)(3)(4)

Background: Decreased genomic and increased gene-specific DNA methylation predispose to colorectal cancer. Dietary folate intake and the methylenetetrahydrofolate reductase polymorphism (MTHFR 677C>T) may influence risk by modifying DNA methylation. Objective: We investigated the associations bet...

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Detalles Bibliográficos
Autores principales: Hanks, Joanna, Ayed, Iyeman, Kukreja, Neil, Rogers, Chris, Harris, Jessica, Gheorghiu, Alina, Liu, Chee Ling, Emery, Peter, Pufulete, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Nutrition 2013
Materias:
Gene-Nutrient Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831541/
https://www.ncbi.nlm.nih.gov/pubmed/24108782
http://dx.doi.org/10.3945/ajcn.113.061432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831541/
https://www.ncbi.nlm.nih.gov/pubmed/24108782
http://dx.doi.org/10.3945/ajcn.113.061432

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