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Involvement of NT3 and P75(NTR) in photoreceptor degeneration following selective Müller cell ablation

BACKGROUND: Neurotrophins can regulate opposing functions that result in cell survival or apoptosis, depending on which form of the protein is secreted and which receptor and signaling pathway is activated. We have recently developed a transgenic model in which inducible and patchy Müller cell ablat...

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Detalles Bibliográficos
Autores principales: Shen, Weiyong, Zhu, Ling, Lee, So-Ra, Chung, Sook H, Gillies, Mark C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831588/
https://www.ncbi.nlm.nih.gov/pubmed/24224958
http://dx.doi.org/10.1186/1742-2094-10-137