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ANRIL/CDKN2B-AS shows two-stage clade-specific evolution and becomes conserved after transposon insertions in simians

BACKGROUND: Many long non-coding RNA (lncRNA) genes identified in mammals have multiple exons and functional domains, allowing them to bind to polycomb proteins, DNA methyltransferases, and specific DNA sequences to regulate genome methylation. Little is known about the origin and evolution of lncRN...

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Detalles Bibliográficos
Autores principales: He, Sha, Gu, Weiling, Li, Yize, Zhu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831594/
https://www.ncbi.nlm.nih.gov/pubmed/24225082
http://dx.doi.org/10.1186/1471-2148-13-247