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The use of high-frequency ultrasound imaging and biofluorescence for in vivo evaluation of gene therapy vectors

BACKGROUND: Non-invasive imaging of the biodistribution of novel therapeutics including gene therapy vectors in animal models is essential. METHODS: This study assessed the utility of high-frequency ultrasound (HF-US) combined with biofluoresence imaging (BFI) to determine the longitudinal impact of...

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Detalles Bibliográficos
Autores principales: Ingram, Nicola, Macnab, Stuart A, Marston, Gemma, Scott, Nigel, Carr, Ian M, Markham, Alexander F, Whitehouse, Adrian, Coletta, P Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831818/
https://www.ncbi.nlm.nih.gov/pubmed/24219244
http://dx.doi.org/10.1186/1471-2342-13-35