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Aldosterone and angiotensin II induce protein aggregation in renal proximal tubules

Renal tubules are highly active transporting epithelia and are at risk of protein aggregation due to high protein turnover and/or oxidative stress. We hypothesized that the risk of aggregation was increased upon hormone stimulation and assessed the state of the intracellular protein degradation syst...

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Detalles Bibliográficos
Autores principales: Cheema, Muhammad U, Poulsen, Ebbe T, Enghild, Jan J, Hoorn, Ewout, Fenton, Robert A, Praetorius, Jeppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831891/
https://www.ncbi.nlm.nih.gov/pubmed/24303148
http://dx.doi.org/10.1002/phy2.64