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Three-dimensional electron crystallography of protein microcrystals
We demonstrate that it is feasible to determine high-resolution protein structures by electron crystallography of three-dimensional crystals in an electron cryo-microscope (CryoEM). Lysozyme microcrystals were frozen on an electron microscopy grid, and electron diffraction data collected to 1.7 Å re...
Autores principales: | Shi, Dan, Nannenga, Brent L, Iadanza, Matthew G, Gonen, Tamir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831942/ https://www.ncbi.nlm.nih.gov/pubmed/24252878 http://dx.doi.org/10.7554/eLife.01345 |
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