New insights into inhibition of human immunodeficiency virus type 1 replication through mutant tRNA(Lys3)

BACKGROUND: Host cellular tRNA(Lys3) is exclusively utilized by human immunodeficiency virus type 1 (HIV-1) as a primer for the replication step of reverse transcription (RTion). Consequently, the priming step of HIV-1 RT constitutes a potential target for anti-HIV-1 intervention. Previous studies i...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Chengxiang, Nerurkar, Vivek R, Lu, Yuanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832253/
https://www.ncbi.nlm.nih.gov/pubmed/24156557
http://dx.doi.org/10.1186/1742-4690-10-112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832253/
https://www.ncbi.nlm.nih.gov/pubmed/24156557
http://dx.doi.org/10.1186/1742-4690-10-112

Ejemplares similares