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New insights into inhibition of human immunodeficiency virus type 1 replication through mutant tRNA(Lys3)

BACKGROUND: Host cellular tRNA(Lys3) is exclusively utilized by human immunodeficiency virus type 1 (HIV-1) as a primer for the replication step of reverse transcription (RTion). Consequently, the priming step of HIV-1 RT constitutes a potential target for anti-HIV-1 intervention. Previous studies i...

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Detalles Bibliográficos
Autores principales:	Wu, Chengxiang, Nerurkar, Vivek R, Lu, Yuanan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832253/ https://www.ncbi.nlm.nih.gov/pubmed/24156557 http://dx.doi.org/10.1186/1742-4690-10-112

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