Mammalian Diaphanous-Related Formin 1 Regulates GSK3β-Dependent Microtubule Dynamics Required for T Cell Migratory Polarization

The mammalian diaphanous-related formin (mDia1), a Rho-regulated cytoskeletal modulator, has been shown to promote T lymphocyte chemotaxis and interaction with antigen presenting cells, but the mechanisms underpinning mDia1 roles in these processes have not been defined. Here we show that mDia1(-/-)...

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Detalles Bibliográficos
Autores principales: Dong, Baoxia, Zhang, Steven S., Gao, Wen, Su, Haichun, Chen, Jun, Jin, Fuzi, Bhargava, Ajay, Chen, Xiequn, Jorgensen, Lars, Alberts, Arthur S., Zhang, Jinyi, Siminovitch, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832380/
https://www.ncbi.nlm.nih.gov/pubmed/24260404
http://dx.doi.org/10.1371/journal.pone.0080500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832380/
https://www.ncbi.nlm.nih.gov/pubmed/24260404
http://dx.doi.org/10.1371/journal.pone.0080500

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