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Mice Expressing RHAG and RHD Human Blood Group Genes

Anti-RhD prophylaxis of haemolytic disease of the fetus and newborn (HDFN) is highly effective, but as the suppressive mechanism remains uncertain, a mouse model would be of interest. Here we have generated transgenic mice expressing human RhAG and RhD erythrocyte membrane proteins in the presence a...

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Detalles Bibliográficos
Autores principales: Goossens, Dominique, da Silva, Nelly, Metral, Sylvain, Cortes, Ulrich, Callebaut, Isabelle, Picot, Julien, Mouro-Chanteloup, Isabelle, Cartron, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832391/
https://www.ncbi.nlm.nih.gov/pubmed/24260394
http://dx.doi.org/10.1371/journal.pone.0080460