Inhibition of phosphodiesterase 4 modulates cytokine induction from toll like receptor activated, but not rhinovirus infected, primary human airway smooth muscle

BACKGROUND: Virus-induced exacerbations of Chronic Obstructive Pulmonary Disease (COPD) are a significant health burden and occur even in those receiving the best current therapies. Rhinovirus (RV) infections are responsible for half of all COPD exacerbations. The mechanism by which exacerbations oc...

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Detalles Bibliográficos
Autores principales: Van Ly, David, De Pedro, Monique, James, Peter, Morgan, Lucy, Black, Judith L, Burgess, Janette K, Oliver, Brian GG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832400/
https://www.ncbi.nlm.nih.gov/pubmed/24237854
http://dx.doi.org/10.1186/1465-9921-14-127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832400/
https://www.ncbi.nlm.nih.gov/pubmed/24237854
http://dx.doi.org/10.1186/1465-9921-14-127

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