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Inhibition of phosphodiesterase 4 modulates cytokine induction from toll like receptor activated, but not rhinovirus infected, primary human airway smooth muscle
BACKGROUND: Virus-induced exacerbations of Chronic Obstructive Pulmonary Disease (COPD) are a significant health burden and occur even in those receiving the best current therapies. Rhinovirus (RV) infections are responsible for half of all COPD exacerbations. The mechanism by which exacerbations oc...
Autores principales: | Van Ly, David, De Pedro, Monique, James, Peter, Morgan, Lucy, Black, Judith L, Burgess, Janette K, Oliver, Brian GG |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832400/ https://www.ncbi.nlm.nih.gov/pubmed/24237854 http://dx.doi.org/10.1186/1465-9921-14-127 |
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