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HIF-1α 1772 C/T and 1790 G/A Polymorphisms Are Significantly Associated with Higher Cancer Risk: An Updated Meta-Analysis from 34 Case-Control Studies

BACKGROUND: HIF-1 activates various genes in cancer progression and metastasis. HIF-1α 1772 C/T and 1790 G/A polymorphisms are reportedly associated with cancer risk; however, the results are inconclusive. METHODOLOGY/PRINCIPAL FINDINGS: A meta-analysis of 34 studies that involved 7522 cases and 984...

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Detalles Bibliográficos
Autores principales: Yang, Xi, Zhu, Hong-Cheng, Zhang, Chi, Qin, Qin, Liu, Jia, Xu, Li-Ping, Zhao, Lian-Jun, Zhang, Qu, Cai, Jing, Ma, Jian-Xin, Cheng, Hong-Yan, Sun, Xin-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832403/
https://www.ncbi.nlm.nih.gov/pubmed/24260383
http://dx.doi.org/10.1371/journal.pone.0080396