Robust Expression of the Human Neonatal Fc Receptor in a Truncated Soluble Form and as a Full-Length Membrane-Bound Protein in Fusion with eGFP

Studies on the neonatal Fc receptor (FcRn) have revealed a multitude of important functions in mammals, including protection of IgG and serum albumin (SA) from lysosomal degradation. The pharmacokinetic behavior of therapeutic antibodies, IgG-Fc- and SA-containing drugs is therefore influenced by th...

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Detalles Bibliográficos
Autores principales: Seijsing, Johan, Lindborg, Malin, Löfblom, John, Uhlén, Mathias, Gräslund, Torbjörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832405/
https://www.ncbi.nlm.nih.gov/pubmed/24260574
http://dx.doi.org/10.1371/journal.pone.0081350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832405/
https://www.ncbi.nlm.nih.gov/pubmed/24260574
http://dx.doi.org/10.1371/journal.pone.0081350

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