Antagonist Properties of Conus parius Peptides on N-Methyl-D-Aspartate Receptors and Their Effects on CREB Signaling

Three members of a family of small neurotoxic peptides from the venom of Conus parius, conantokins (Con) Pr1, Pr2, and Pr3, function as antagonists of N-methyl-D-aspartate receptors (NMDAR). We report structural characterizations of these synthetic peptides, and also demonstrate their antagonistic p...

Descripción completa

Detalles Bibliográficos
Autores principales: Kunda, Shailaja, Cheriyan, John, Hur, Michael, Balsara, Rashna D., Castellino, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832412/
https://www.ncbi.nlm.nih.gov/pubmed/24260577
http://dx.doi.org/10.1371/journal.pone.0081405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832412/
https://www.ncbi.nlm.nih.gov/pubmed/24260577
http://dx.doi.org/10.1371/journal.pone.0081405

Ejemplares similares