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Antagonist Properties of Conus parius Peptides on N-Methyl-D-Aspartate Receptors and Their Effects on CREB Signaling

Three members of a family of small neurotoxic peptides from the venom of Conus parius, conantokins (Con) Pr1, Pr2, and Pr3, function as antagonists of N-methyl-D-aspartate receptors (NMDAR). We report structural characterizations of these synthetic peptides, and also demonstrate their antagonistic p...

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Detalles Bibliográficos
Autores principales:	Kunda, Shailaja, Cheriyan, John, Hur, Michael, Balsara, Rashna D., Castellino, Francis J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832412/ https://www.ncbi.nlm.nih.gov/pubmed/24260577 http://dx.doi.org/10.1371/journal.pone.0081405

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