Multiple Transcripts from a 3′-UTR Reporter Vary in Sensitivity to Nonsense-Mediated mRNA Decay in Saccharomyces cerevisiae

Nonsense-mediated mRNA decay (NMD) causes accelerated transcript degradation when a premature translation termination codon disrupts the open reading frame (ORF). Although endogenous transcripts that have uninterrupted ORFs are typically insensitive to NMD, some can nonetheless become prone to NMD w...

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Detalles Bibliográficos
Autores principales: Zaborske, John M., Zeitler, Bethany, Culbertson, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832414/
https://www.ncbi.nlm.nih.gov/pubmed/24260526
http://dx.doi.org/10.1371/journal.pone.0080981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832414/
https://www.ncbi.nlm.nih.gov/pubmed/24260526
http://dx.doi.org/10.1371/journal.pone.0080981

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