Thrombolytic Effects of the Snake Venom Disintegrin Saxatilin Determined by Novel Assessment Methods: A FeCl(3)-Induced Thrombosis Model in Mice

Saxatilin, a novel disintegrin purified and cloned from the venom of the Korean snake Gloydius saxatilis, strongly inhibits activation and aggregation of platelets. Glycoprotein (GP) IIb/IIIa receptor antagonists can resolve thrombus, so saxatilin might also have thrombolytic effects. We investigate...

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Detalles Bibliográficos
Autores principales: Kwon, Il, Hong, Sung-Yu, Kim, Young Dae, Nam, Hyo Suk, Kang, Sungsoo, Yang, Seung-Hee, Heo, Ji Hoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832438/
https://www.ncbi.nlm.nih.gov/pubmed/24260554
http://dx.doi.org/10.1371/journal.pone.0081165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832438/
https://www.ncbi.nlm.nih.gov/pubmed/24260554
http://dx.doi.org/10.1371/journal.pone.0081165

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