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Ubiquitin-Specific Proteases 25 Negatively Regulates Virus-Induced Type I Interferon Signaling
Ubiquitination and deubiquitination have emerged as critical regulatory processes in the virus-triggered type I interferon (IFN) induction pathway. In this study, we carried out a targeted siRNA screen of 54 ubiquitin-specific proteases (USPs) and identified USP25 as a negative regulator of the viru...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832446/ https://www.ncbi.nlm.nih.gov/pubmed/24260525 http://dx.doi.org/10.1371/journal.pone.0080976 |