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Evaluation of OspA Vaccination-Induced Serological Correlates of Protection against Lyme Borreliosis in a Mouse Model
BACKGROUND: For clinical development of a novel multivalent OspA vaccine against Lyme borreliosis, serological assays are required which can be used to establish immune correlates of protection against infection with Borrelia. METHODS: Four assays (an OspA IgG ELISA, a competitive inhibition (CI) EL...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832494/ https://www.ncbi.nlm.nih.gov/pubmed/24260146 http://dx.doi.org/10.1371/journal.pone.0079022 |