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Evaluation of OspA Vaccination-Induced Serological Correlates of Protection against Lyme Borreliosis in a Mouse Model

BACKGROUND: For clinical development of a novel multivalent OspA vaccine against Lyme borreliosis, serological assays are required which can be used to establish immune correlates of protection against infection with Borrelia. METHODS: Four assays (an OspA IgG ELISA, a competitive inhibition (CI) EL...

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Detalles Bibliográficos
Autores principales:	Schwendinger, Michael G., O'Rourke, Maria, Traweger, Andreas, Savidis-Dacho, Helga, Pilz, Andreas, Portsmouth, Daniel, Livey, Ian, Barrett, P. Noel, Crowe, Brian A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832494/ https://www.ncbi.nlm.nih.gov/pubmed/24260146 http://dx.doi.org/10.1371/journal.pone.0079022

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